Natural Hormone Replacement Therapy For Menopause

Natural Hormone Replacement Therapy Definition

Natural hormone replacement therapy (NHRT) is exactly what the name implies – using non-synthetic substances that are identical to hormones but derived from plant substances to treat various hormone problems.

Natural Hormone Replacement Therapy Origins

Phytohormones have been used in Chinese medicine for thousands of years. Natural progesterone was first crystallized from plants in 1938. Oral contraceptives were originally derived from wild yam; soy was also used in the production of contraceptive hormones. Researchers developed NHRT by the late 1970s, and it was commercially available a few years later. As patients became increasingly dissatisfied with conventional treatments, use of natural regimens increased.

Natural Hormone Replacement Therapy Benefits

Human bodies, as they age, are sometimes subject to falling hormone levels. Disorders thought to be related to low hormone levels include bone loss and osteoporosis, heart disease, cancer, high cholesterol, cancer, and Alzheimer’s disease. NHRT often alleviates symptoms of hormone imbalances and deficiencies. Best-known is the ability of NHRT to help maintain hormone balance in the body during and after menopause, when estrogens, progesterone and testosterone decline. Andropause, which is the result of falling testosterone levels and can often affect men in middle age, can benefit from similar treatment. Menopausal and andropausal symptoms frequently improve after one to three months of NHRT.

Some studies suggest that NHRT may also assist in preventing fibroblastic or lumpy breasts, as well as generally slowing the aging process. It also seems to benefit middle-aged men, helping to increase muscle mass, energy levels, and sex drive, and to improve concentration.

For more information about Natural Hormone Replacement Therapy Click Here

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Lower Cholesterol Naturally With Foods

New Study: Combination of Cholesterol-lowering Foods Works Better for Lowering LDL than Diet of Low Saturated Fats.

People trying to lower their low-density lipoprotein cholesterol levels (LDL-C) do better over a 6-month period when urged to eat a diet that combines cholesterol-lowering foods (nuts, soy protein, plant sterols, etc.) than they do when counseled to use a low-saturated fat diet, according to a new study in the most recent issue of the Journal of the American Medical Association (JAMA).

The background information section of the article explains that this Canadian study is the first systematic attempt to compare the effects of using known cholesterol-lowering foods in a therapeutic diet for high serum cholesterol patients with the effects of more conventional low-fat diets. Interest in including such foods, either singly or in combination, i.e. a dietary portfolio, has been part of ongoing attempts to improve diet therapy for such patients.

The project, conducted in multiple medical centers across Canada by a team headed by David J. A. Jenkins, M.D., of St. Michael’s Hospital and the University of Toronto, attempted to discover whether such a diet caused LDL-C levels to significantly decrease when compared with a control low-saturated fat diet, after a 6-month follow-up period. Although the control diet had ample amounts of whole grains and high fiber foods, it did not have the plant sterols, nuts, viscous fiber, and soy protein – all listed as cholesterol lowering by the U.S. Food & Drug Administration – of the experimental diet. The study followed 351 patients with hyperlipidemia at 4 academic medical centers in Toronto, Quebec City,Winnipeg, and Vancouver, in evaluations conducted between June 2007 and February 2009, using 1 of 3 possible treatment regimes.

The participating patients received diet counseling for 6 months for either (1) the conventional low-saturated fat control diet, or (2) a “routine” experimental dietary portfolio regime with including 2 clinic visits during the 6 months, or (3) an “intensive” experimental portfolio regime with 7 clinic visits.

The report gives a modified intention-to-treat analysis of 345 participants, which shows an overall attrition rate that did not differ significantly between the 3 treatments, at 18% for the intensive portfolio, 23% for the routine portfolio, and 26% for the control diet group.

The control diet group showed LDL-C levels that decreased, during the period from inception to week 24, by –3.0 % (-8 mg/dL). The groups counseled to eat the experimental cholesterol-lowering diet showed, for the routine portfolio group, decreased levels of -13.1% (-24 mg/dL) and for the intensive portfolio group, -13.8% (-26mg/dL).

The study authors write, “Percentage LDL-C reductions for each dietary portfolio were significantly more than the control diet. The 2 dietary portfolio interventions did not differ significantly. Among participants randomized to one of the dietary portfolio interventions, percentage reduction in LDL-C on the dietary portfolio was associated with dietary adherence.”

They sum up, “In conclusion, this study indicated the potential value of using recognized cholesterol-lowering foods in combination. We believe this approach has clinical application. A meaningful 13 percent LDL-C reduction can be obtained after only 2 clinic visits of approximately 60-and 40-minute sessions. The limited 3 percent LDL-C reduction observed in the conventional diet is likely to reflect the adequacy of the baseline diet and therefore suggests that larger absolute reductions in LDL-C may be observed when the dietary portfolio is prescribed to patients with diets more reflective of the general population.”

Source: August 23, 2011, Science Daily.

To lower your cholesterol naturally without medication contact me today by calling 201.618.3534 or email me at Rob@DrRobertG.com

 

Hypnosis Works To Help Smokers Quit

Learn more about my Stop Smoking Program Click Here

Smokers who want to quit the habit and try nicotine patches may find that the patches aren’t helping to control their craving for tobacco. The effectiveness of patches, unfortunately, varies from individual to individual. However, a study completed in 2008 indicates that the usefulness of nicotine patches can be improved if they’re used along with therapeutic hypnosis (a similar improvement in patch effectiveness has been shown when they’re combined with professional counseling). The study found specifically that hypotherapy worked just as well as standard behavioral counseling in combination with nicotine patches, to aid quitting smokers in staying off cigarettes for one year.

The study’s lead author, Timothy Carmody, said, “This study provides much-needed evidence that hypnosis is indeed a very helpful treatment.”

Carmody described the hypotherapeutic method, in which the patient is guided into a relaxed state by a therapist, and then inculcated with mental training skills meant to help them deal with the desire to smoke and with withdrawal symptoms. Patients also receive an audiotape of the training session to use at home when needed. The looked-for result is an increasing confidence that they can and will stop smoking, and stay off tobacco for good. This method is among several alternative therapies that top hospitals and research institutes have increasingly been accepting and using.

The study was done at San Francisco VA Medical Center and the University of California-San Francisco, and its results published in the May 2008 issue of Nicotine & Tobacco Research. The 286 subjects were split randomly into two groups, one receiving standard behavioral counseling and the other hypnotherapy. In behavioral counseling, discussions were conducted between patient and therapist about the dangerous effects of smoking and the benefits of smoking cessation. In both groups, the patients had two hour-long therapy sessions and then received 20-minute follow-up calls from their therapists, reinforcing the ideas that had been conveyed either through standard counseling or during the hypnotized state.

It was discovered that patients who reported having been depressed in the past found the hypnotherapy especially helpful. Carmody said that this finding may point to the usefulness of using hypnotherapy with quitting smokers who have a history of depression and perhaps other psychiatric problems.

This research was characterized as encouraging by Brian Hitsman, assistant professor of preventive medicine at Northwestern University’s Feinberg School of Medicine, who said that hypnotherapy like that used in the study may prove to be a non-pharmocological therapy for quitting smokers that is as helpful as standard counseling. He cautioned that the question of hypnosis’ effectiveness if used alone is still open, saying, “This study says nothing about the potential effect of the hypnosis intervention in the absence of a nicotine patch.”

The field of smoking cessation therapy is evolving rapidly. Future questions for research will center on the effectiveness of counseling and/or hypnotherapy if the patient stays with them for a longer term, more than one year, according to Prof. Hitsman. In his opinion, nicotine addiction ought to be treated like a chronic condition, similar to the way a disease like diabetes is approached. “For most people, smoking begins in adolescence and persists across the life span, with multiple periods of remission and relapse. Acute care is the current model, with treatments typically given up to 12 weeks. For many, successful cessation will require ongoing intervention.”

Robert Galarowicz ND
Stop Smoking Professional
Bergen County New Jersey
201.618.3534

Herbs May Not Be Safe For You … New Jersey Naturopath Explains

Many Herbal Products Fail to Provide Important Safety Info, UK Study Finds

This study shows why you need a trained professional to ensure your safety when using herbs…

Many of the herbal preparations that can be purchased over the counter in health food stores and at drugstores still do not give important safe usage information on their packages, say researchers at the University of Leeds in the UK.

Earlier in 2011, the European Union passed new legislation requiring information on possible side effects to be given on packaging of traditional herb-based products like echinacea and St. John’s wort. In addition they must show clear information about possible interactions with prescription medicines and the adviseability of their use for people with specific illnesses. They have to be marked with a “THR” logo, indicating “Traditional Herbal Registration”.

There are, however, several well-known remedies like ginkgo and Asian ginseng that do not necessarily fall under this new law, and which may not show these important safety details. Another problem is older stocks of herbal products on store shelves which were packaged before the law was passed, and may also be missing safety cautions.

The University of Leeds team discovered that before the law came into force in April 2011, most “OTC” herbal products had none of the safety information now required. Professor of Pharmacy Theo Raynor, the lead researcher, says that the buying public has no assurance that the new law is making much difference at present.

“The best advice to consumers is ‘buyer beware’, as it always has been. Many people believe herbal medicines are somehow different to other medicines because they are ‘natural’. However, any substance that affects the body — no matter where it came from — has the potential to do harm if it is not taken correctly,” he cautioned.

The Leeds team bought 68 separate preparations of five well-known herbs (echinacea, St. John’s wort, Asian ginseng, ginkgo, and garlic) at a range of retailers – three large chain pharmacies, three supermarket pharmacies, and two large health food stores. All of the herbs chosen have been shown to cause harmful effects in some persons in some circumstances.

For example, ginkgo can increase bleeding risks, echinacea can bring on allergic reactions, St. John’s wort can reduce the efficacy of contraceptive pills, and Asian ginseng should not be taken by diabetics. Something as common as garlic can have problematic effects in some cases, as it thins the blood and may interfere with HIV therapy.

The product information on the purchased herbs was compared to information for these substances from the US National Center for Complementary and Alternative Medicine. The study evaluated the accuracy and completeness of the information the products gave about drug interactions, precautions for those with specific illnesses, and possible side effects.

The results, published in BioMed Central’s open access journal BMC Medicine, show that 93% of the purchased products were unlicensed, which means that they were not legally required to come up to product safety informations standards. Over half of these were being sold as food supplements. Just 13% had an information sheet included in the packaging, and only three products gave an acceptable amount of safety information.

Professor Raynor stated, “Consumers need reliable and comprehensive information when buying herbal medicines — information which tells them whether it is suitable for them. I would advise anyone buying a herbal medicine to check that the box or packaging contains the ‘THR’ logo, which shows that the information it comes with has been approved.

“Herbal medicines should, ideally, be purchased where trained staff are available, so that consumers can have any questions answered. This information should be available from pharmacists. People should also always tell their doctor about herbal medicines they are taking, so they receive the best possible care.”

August 9, 2011, Science Daily.

Arthritis Inflammation Increases Possibiliy of Heart Disease..

To learn more about my arthritis and heart health services go to home page at www.drrobertg.com

People who have rheumatoid arthritis (RA) are more likely to die of cardiovascular disease than those who don’t have the condition, according to a newly published 5-year study. The results of the study have been published in BioMed Central’s open access journal Arthritis Research & Therapy. They show that RA sufferers’ higher risk results from the inflammation caused by RA. When the arthritis is treated with disease modifying antirheumatic drugs (DMARDs), the heart disease risk is also reduced.

The study followed over 400 people with RA for 5 years starting from the date of their diagnosis,  and tracked their RA’s progression by using chemical markers of inflammation, and evaluating physical appearance. Researchers followed treatment methods and tabulated other heart disease risk factors that are common to the whole population such as weight, blood pressure, cholesterol level, smoking, and diabetes.

Ninety-seven percent of patients had received DMARD therapy after 5 years. The medications lessened both the chemical markers caused by arthritic inflammation and the visual signs of arthritis. In addition, the participants were taking better care of themselves, as the number of smokers in the group decreased, their BMI had gone down, and their blood pressure figures lowered (this partly due to anti-high blood pressure treatments).

When the data from patients was analyzed, it was seen that new cardiovascular events such as strokes, heart attacks, or DVTs correlated with the severity of their arthritis and whether they had diabetes, high blood pressure and/or high triglycerides. The researchers found encouraging evicence that DMARDs lowered the risk for such events, while COX-2 inhibitors apparently predicted new events.

Source: August 15, 2011, Science Daily.

Antioxidant Spices Are Good For You

Unhealthy Effects of Fatty Foods Lowered with Antioxidant Spices.

The body’s negative reactions to high-fat meals are reduced by the use of antioxidant spices like turmeric and cinnamon, reports a new  study by researchers from Penn State.

Sheila West, associate professor of biobehavioral health at Penn State and lead author of the study, said, “Normally, when you eat a high-fat meal, you end up with high levels of triglycerides, a type of fat, in your blood. If this happens too frequently, or if triglyceride levels are raised too much, your risk of heart disease is increased. We found that adding spices to a high-fat meal reduced triglyceride response by about 30 percent, compared to a similar meal with no spices added.”

Six men, aged between 30 and 65, who were overweight but otherwise in good health, were served meals prepared by the research team on two separate days during the study. The test meal was chicken curry, Italian herb bread, and a cinnamon biscuit, to which two tablespoons of culinary spices had been added. The control meal was the same, but no spices were used. After they had eaten, the participants had blood drawn every half hour for three hours. The findings were published in the current issue of the Journal of Nutrition.

Ann Skulas-Ray, postdoctoral fellow and team member, described the spices. “In the spiced meal, we used rosemary, oregano, cinnamon, turmeric, black pepper, cloves, garlic powder and paprika. We selected these spices because they had potent antioxidant activity previously under controlled conditions in the lab.”

After eating the spiced meal, the men showed antioxidant blood activity 13% above levels recorded after the control meal, and insulin response lower by about 20%.

According to West, many scientists think that oxidative stress contributes to heart disease, arthritis and diabetes. “Antioxidants, like spices, may be important in reducing oxidative stress and thus reducing the risk of chronic disease,” she said, adding that the spice dose they used provided the equivalent amount of antioxidants contained in 5 ounces of red wine or 1.4 ounces of dark chocolate.

Current thinking among many scientists in the field, says West, is that oxidative stress is a factor in heart disease, diabetes, and arthritis. She said, “Antioxidants like spices may be important in reducing oxidative stress and thus reducing the risk of chronic disease”, and added that the amounts of spice used in the test had antioxidant value similar to 5 ounces of red wine or 1.5 ounces of dark chocolate.

No stomach distress was experienced by the subjects who ate the food with 2 tablespoons of spices, said Skulas-Ray. “They enjoyed the food and had no gastrointestinal problems.” She added, “The participants were notified ahead of time that they would be eating highly spiced foods and they were willing to do so.”

West’s plan for future study includes discovering whether similar results can be obtained with smaller spice amounts.

Besides West, other Penn State researchers in this study include: Ann Skulas-Ray, graduate student; Penny Kris-Etherton, Distinguished Professor of Nutrition; Danette Teeter, former research assistant; and John Vanden Heuvel, professor of veterinary science. Chung-Yen (Oliver) Chen, scientist, Tufts University, also was involved in the study. The study received support from The McCormick Science Institute and National Institutes of Health.

Source: August 11, 2011, Science Daily.

Vegetarian Diet And Kidney Disease

Recent Study: Kidney Disease Patients on Vegetarian Diet Can Lower Blood, Urine Phosphorus Levels

Kidney disease patients who maintain a vegetarian diet see their phosphorus levels descend dramatically, a recent study showed. The results were scheduled for publication in the Clinical Journal of the American Society of Nephrology (CJASN). They suggest that patients with kidney disease can prevent the toxic accumulation of phosphorus in their bodies by eating vegetables and eliminating meat.

An inability to rid the body of extra phosphorus – a common food additive, and a common element in proteins – is characteristic of kidney disease. Because high phosphorus levels can bring on fatal heart disease, kidney disease sufferers must be careful to keep their intake of the mineral down. This can be difficult; though chronic kidney disease (CKD) patients are advised by doctors to keep to a low phosphorus diet, the amounts of the mineral is not shown on food labels.

The current study of vegetarian vs. meat-containing diets was done by Sharon Moe, MD (Indiana University School of Medicine and Roudebush Veterans’ Affairs Medical Center) and her colleagues. Participating CKD patients ate either a vegetarian or meat-based diet for one week, and then switched diets between two and four weeks later. Each week-long regime was followed by blood and urine testing.

Both diets contained equivalent protein and phosphorus concentration. However, the vegetarian diet patients had decreased blood phosphorus levels and less excreted phosphorus in their urine than did the meat diet patients. The study did not undertake to discover the cause of the difference. But a diet based on grains has a lower protein-to-phosphate ratio than one that contains meat – and a high proportion of those phosphates is in a form, phytate, which the human body does not absorb.

The conclusion reached by the team was that, for CKD patients, there is a strong relationship between the source of dietary proteins and the amount of phosphorus in their bodies. They suggest that CKD patients should receive dietary counseling both about the importance of controlling phosphorus intake and the different protein sources of phosphorus. The study says, “These results, if confirmed in longer studies, provide rationale for recommending a predominance of grain-based vegetarian sources of protein to patients with CKD. This diet would allow increased protein intake without adversely affecting phosphorus levels.”

This study was co-authored with Dr. Moe by: Miriam Zidehsarai, MD, Mary Chambers, RN, Laurie Trevino, MS (Indiana University School of Medicine); Lisa Jackman, MS, J. Scott Radcliffe, PhD (Purdue University); Susan Donahue, MBA, and John Asplin, MD (Litholink, Inc.)

Journal Reference:

1. Sharon M. Moe, Miriam P. Zidehsarai, Mary A. Chambers, Lisa A. Jackman, J. Scott Radcliffe, Laurie L. Trevino, Susan E. Donahue, and John R. Asplin. Vegetarian Compared with Meat Dietary Protein Source and Phosphorus Homeostasis in Chronic Kidney Disease. Clinical Journal of the American Society Nephrology, December 23, 2010 DOI: 10.2215/CJN.05040610

American Society of Nephrology (2010, December 23). Kidney disease patients: Vegetarian diet lowers blood and urine

New Jersey New York Chronic Kidney Disease Treatment Click Here

Natural Relief For IBS That You Can Do At Home

Doctors of holistic medicine have known this for years as there has been many studies published beforehand. The conventional medical doctor in the study acts like he finally put the science behind it…lol  a good study nonetheless and a simple remedy you can try at home. Click here to learn more about my digestive health service.

How Peppermint Helps to Relieve Irritable Bowel Syndrome

A new paper from scientists at the University of Adelaide, Australia, explains how peppermint, long used as a natural remedy, actually acts to relieve Irritable Bowel Syndrome. The paper was published in the journal Pain.

University of Adelaide researchers have shown for the first time how peppermint helps to relieve, which affects up to 20% of the population.

A team of researchers from the University’s Nerve-Gut Research Laboratory described how peppermint activates an “anti-pain” channel in the colon, soothing inflammatory pain in the gastrointestinal tract.

Peppermint has been commonly prescribed by naturopaths for many years, there has been no clinical evidence until now to demonstrate why it is so effective in relieving pain, said Dr Stuart Brierley. “Our research shows that peppermint acts through a specific anti-pain channel called TRPM8 to reduce pain sensing fibers, particularly those activated by mustard and chili. This is potentially the first step in determining a new type of mainstream clinical treatment for Irritable Bowel Syndrome (IBS).”

IBS, a gastrointestinal disorder, affects about 20% of Australians and costs millions of dollars each year in lost productivity, work absenteeism and health care. It causes abdominal pain, bloating, diarrhea and/or constipation.

“This is a debilitating condition and affects many people on a daily basis, particularly women who are twice as likely to experience Irritable Bowel Syndrome,” Dr Brierley says.

“Some people find their symptoms appear after consuming fatty and spicy foods, coffee and alcohol, but it is more complex than that. There appears to be a definite link between IBS and a former bout of gastroenteritis, which leaves nerve pain fibers in a heightened state, altering mechanisms in the gut wall and resulting in ongoing pain.”

According to Dr Brierley, recent floods in Queensland and Victoria could result in a spike of gastroenteritis cases in Australia due to contaminated water supplies. Case studies in Europe and Canada showed that those who contracted gastroenteritis from contaminated water supplies often experienced IBS symptoms that persisted for at least eight years.

IBS can be triggered by food poisoning, stress, a reaction to antibiotics, gastroenteritis and food intolerance, and in some cases is genetic. Symptoms often fade and then recur over a lifetime, but there is no cure.

Dr Brierley is one of 25 researchers who work to find treatments for intestinal diseases at the University of Adelaide’s Nerve-Gut Research Laboratory.

Source: ScienceDaily (Apr. 20, 2011) —

I see a large percentage of people with Irritable Bowel Syndrome who come all throughout NJ New Jersey NY New York and Hudson, Bergen, Passaic, Essex, Union, Rockland, Orange Counties.

Kidney Failure Reversed With Low Carb Diet

A study that shows what diet can do for kidney failure. I wouldn’t recommend anyone with kidney disease to go on this type of diet but there are diets available that are just as effective. Click  here to learn more…

Diabetics’ Kidney Failure May Be Reversed by Low Carb Diet

Mt. Sinai School of Medicine researchers have completed a study that provides the first conclusive evidence that a special high-fat, low-carbohydrate diet, known as a ketogenic diet, may be able to reverse damaged kidney functioning in Type 1 and Type 2 diabetic patients. In addition, the researchers identified a panel of genes, previously unreported, that is associated with kidney failure related to diabetes. The expression of these genes was reversed by the ketogenic diet.

Mice that had been bred to be genetically prone to Type 1 and Type 2 diabetes were studied by Charles Mobbs, PhD, Professor of Neuroscience and Geriatrics and Palliative Care Medicine at Mount Sinai School of Medicine, and his research team. The diabetic mice developed diabetic kidney failure (nephropathy) and were divided into two groups; one was maintained on a regular high carbohydrate diet, and the other was switched to a ketogenic diet. The latter group showed reversed kidney failure after 8 weeks.

Dr. Mobbs states, “Our study is the first to show that a dietary intervention alone is enough to reverse this serious complication of diabetes. This finding has significant implications for the tens of thousands of Americans diagnosed with diabetic kidney failure, and possibly other complications, each year.”

The ketogenic diet is high in fats, low in carbohydrates, and contains a moderate quantity of protein; it is often prescribed for seizure control in epileptic children. Ketones are molecules produced by the body when the level of fat in the blood is high but the glucose levels are low; the ketones are then used as an energy source by many body cells instead of glucose, which keeps glucose metabolism low. Because high levels of glucose metabolism lead to kidney failure in diabetics, the researchers put forward the hypothesis that this specialized diet could block the harmful effect of excess glucose. The diet is an extreme one and not a practical long-term solution for adults. But this research shows  that short-term use of the regime – possibly as short as a month – may be enough to “reset” the expression of the newly identified gene panel, and therefore the abnormal physical process leading to kidney failure.

Another array of genes was identified by the team that is expressed in diabetic kidney failure that was not before suspected to play any role in the disease. The genes’ association with diabetic nephropathy is a result of stresses on the functioning of cells. This genetic expression was also reversed in the mice consuming the ketogenic diet.

The research group intends to continue working on the ketogenic diet’s effects and the mechanisms that make it reverse kidney failure, both in diabetics and those suffering age-related nephropathy. Dr. Mobbs speculates that the diet may be valuable in treating neurological diseases, and retinopathy, which causes blindness.

He said, “Knowing how the ketogenic diet reverses nephropathy will help us identify a drug target and subsequent pharmacological interventions that mimic the effect of the diet. We look forward to studying this promising development further.”

This study was funded partly by the National Institutes of Health and by the Juvenile Diabetes Research Foundation

Source: April, 2011. ( Original article from Science Daily).

More People Getting Kidney Disease Due To Diabetes

Higher Incidence of Diabetic Kidney Disease in United States

During the last 20 years, diabetic kidney disease has become more prevalent in direct proportion to the increased incidence of diabetes during the same period, says a study published in the June 22-29, 2011 issue of the Journal of the American Medical Association (JAMA).

The disorder is often found as a complication of diabetes; DKD (diabetic kidney disease) is the commonest cause of chronic kidney disease in the industrial world. About 40% of diabetes sufferers eventually get DKD. DKD is also the cause of almost 50% of new cases of end-stage renal disease (ESRD) in the US. The study’s authors write, “Over time, the prevalence of DKD may increase due to the expanding size of the diabetes population or decrease due to the implementation of diabetes therapies.”

Trends of incidence of DKD in the US over the last twenty years were examined by Ian H. de Boer, M.D., M.S., of the University of Washington, Seattle, and colleagues; they also assessed changes in the way disease manifested itself in diabetics over that period. Data from the Third National Health and Nutrition Examination Survey (NHANES III) from 1988-1994 (n = 15,073), NHANES 1999-2004 (n = 13,045), and NHANES 2005-2008 (n = 9,588) were included in the study. The diabetic participants were classified by levels of hemoglobin A 1c of 6.5 percent or greater, use of glucose-lowering medications, or both (n = 1,431 in NHANES III; n = 1,443 in NHANES 1999-2004; n=1,280 in NHANES 2005-2008). The definition of DKD used was either (a) diabetes with albuminuria (ratio of urine albumin to creatinine 30 mg/g or greater), or (b) impaired glomerular filtration rate (less than 60 mL/min/1.73 m 2 estimated using the Chronic Kidney Disease Epidemiology Collaboration formula), or both.

It was found that the prevalence of diabetic kidney disease in US changed as follows: 2.2% in 1998-94, 2.8% in 1999-2004, and 3.3% in 2005-2008. With the increase demographically adjusted, the increase rates were 18 percent from 1988-1994 to 1999-2004 and 34 percent from 1988-1994 to 2005-2008. The actual estimated number of people suffering DKD in the US at any given point between 1988-1994 was 3.9 million; this estimated number for 1999-2004 was 5.5 million; for 2005-2008, 6.9 million.

The percentage of diabetics who took medications to lower glucose levels went up from 56.2 to 74.2, while the usage percentage of renin-angiotensin-aldosterone system inhibitors rose from 11.2 to 40.6. Rates of impaired GFR increased from 14.9 percent in 1988-1994 to 17.7 percent in 2005-2008. There was a decrease in incidence of impaired albuminuria, from 27.3% to 23.7% during this time span which was not of statistical significance.

The authors sum up, “In conclusion, DKD has become more prevalent in the U.S. population over the last 2 decades and will likely contribute increasingly to health care costs and mortality. Among persons with diabetes, clinical manifestations of DKD shifted to include more impaired GFR but the prevalence of any DKD did not change despite increased use of diabetes-related medications.”

Source: July Sciencedaily

If you are from New Jersey New York or Pennsylvania and have kidney disease you must learn more about my services by clicking here … New Jersey Kidney Disease – New York CKD – NJ – NY Kidney Disease